De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct

We report a case of a patient who developed glioblastoma in the territory of a previous infarction. Two years after an ischemic stroke, the patient presented with a cystic, necrotic, and heterogeneously enhancing mass. Open biopsy and debulking of the mass with histological analysis revealed the mas...

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Bibliographic Details
Main Authors: Teresa J. Wojtasiewicz, Andrew F. Ducruet, Sonal S. Noticewala, Peter Canoll, Guy M. McKhann
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2013/356526
Description
Summary:We report a case of a patient who developed glioblastoma in the territory of a previous infarction. Two years after an ischemic stroke, the patient presented with a cystic, necrotic, and heterogeneously enhancing mass. Open biopsy and debulking of the mass with histological analysis revealed the mass to be glioblastoma. Though several cases of posttraumatic GBM have been reported, this is the first proposed case of GBM after an ischemic stroke. From this case, we suggest that the ischemic stroke, like other forms of cortical injury, may predispose to glioblastoma formation.
ISSN:2090-6668
2090-6676