Testis-expressed profilins 3 and 4 show distinct functional characteristics and localize in the acroplaxome-manchette complex in spermatids

<p>Abstract</p> <p>Background</p> <p>Multiple profilin isoforms exist in mammals; at least four are expressed in the mammalian testis. The testis-specific isoforms profilin-3 (PFN3) and profilin-4 (PFN4) may have specialized roles in spermatogenic cells which are distin...

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Bibliographic Details
Main Authors: Rothkegel Martin, Cappallo-Obermann Heike, Kursula Petri, Murk Kai, Behnen Martina, Kierszenbaum Abraham L, Kirchhoff Christiane
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/10/34