Induction of Regulatory Properties in the Intestinal Immune System by Dimethyl Fumarate in Lewis Rat Experimental Autoimmune Neuritis

Objective: Dimethyl fumarate (DMF) exerts immunomodulatory and neuroprotective effects in the animal model of experimental autoimmune neuritis (EAN) in the Lewis rat. DMF has been shown to modulate gut microbiota in veterinary medicine, however the effects of oral DMF on the gut-associated lymphoid...

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Bibliographic Details
Main Authors: Kalliopi Pitarokoili, Hussein Bachir, Melissa Sgodzai, Thomas Grüter, Steffen Haupeltshofer, Alexander Duscha, Xiomara Pedreiturria, Jeremias Motte, Ralf Gold
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02132/full