An Investigation of the Effect of Transfected Defective, Ebola Virus Genomes on Ebola Replication

An Investigation of the Effect of Transfected Defective, Ebola Virus Genomes on Ebola Replication

As the ongoing outbreak in the Democratic Republic of Congo illustrates, Ebola virus disease continues to pose a significant risk to humankind and this necessitates the continued development of therapeutic options. One option that warrants evaluation is that of defective genomes; these can potential...

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Bibliographic Details
Main Authors: Sophie J. Smither, Isabel Garcia-Dorival, Lin Eastaugh, James S. Findlay, Lyn M. O'Brien, Jonathan Carruthers, E. Diane Williamson, Carmen Molina-París, Julian A. Hiscox, Thomas R. Laws
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
ebola
defective interfering particles
DIPs
deletion
in vitro
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00159/full

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