A modular system to evaluate the efficacy of protease inhibitors against HIV-2.

A modular system to evaluate the efficacy of protease inhibitors against HIV-2.

The human immunodeficiency virus (HIV) protease is a homodimeric aspartyl protease that is crucial for the viral life-cycle, cleaving proviral polyproteins, hence creating mature protein components that are required for the formation of an infectious virus. With diagnostic measures and clinically us...

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Bibliographic Details
Main Authors: Mohamed Mahdi, Krisztina Matúz, Ferenc Tóth, József Tőzsér
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4242608?pdf=render

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