Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective
<p>Abstract</p> <p>Background</p> <p>A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes a small fraction of the interface, it is vital to the stability o...
Main Authors: | Li Jinyan, Liu Qian |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-05-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/11/244 |
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