Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake.
Human sodium/iodide symporter (hNIS) protein is a membrane glycoprotein that transports iodide ions into thyroid cells. The function of this membrane protein is closely regulated by post-translational glycosylation. In this study, we measured glycosylation-mediated changes in subcellular location of...
Main Authors: | Taemoon Chung, Hyewon Youn, Chan Joo Yeom, Keon Wook Kang, June-Key Chung |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4658105?pdf=render |
Similar Items
-
Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells.
by: Zhi Liu, et al.
Published: (2012-01-01) -
Relationship between Apoptosis Imaging and Radioiodine Therapy in Tumor Cells with Different Sodium Iodide Symporter Gene Expression
by: Kyung Oh Jung, et al.
Published: (2015-01-01) -
In Vivo Scintigraphic Imaging of Antitumor Effects by Combined Radioiodine Therapy and Human Sodium Iodide Symporter Gene Immunotherapy
by: Yun Choi, et al.
Published: (2010-05-01) -
Targeted delivery of the theranostic sodium iodide symporter (NIS) for cancer gene therapy
by: Grünwald, Geoffrey
Published: (2013) -
The sodium iodide symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue.
by: James Ryan, et al.
Published: (2011-01-01)