Role of short-wavelength blue light in the formation of cataracts and the expression of caspase-1, caspase-11, Gasdermin D in rat lens epithelial cells: insights into a novel pathogenic mmechanism of cataracts

Role of short-wavelength blue light in the formation of cataracts and the expression of caspase-1, caspase-11, Gasdermin D in rat lens epithelial cells: insights into a novel pathogenic mmechanism of cataracts

Abstract Background With the popularity of blue-rich light-emitting diode (LED)-backlit display devices, our eyes are now exposed to more short-wavelength blue light than they were in the past. The goal of this study was to investigate the pathogenesis of cataracts after short-wavelength light expos...

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Bibliographic Details
Main Authors: Yamin Wang, Min Zhang, Ying Sun, Xiaohui Wang, Zhaowei Song, Huazhang Li, Kexin Liu, Zhijian Li
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Ophthalmology
Subjects:
Pyroptosis
Short-wavelength blue light
Caspase-1/11
GSDMD
Cataract
Online Access:http://link.springer.com/article/10.1186/s12886-020-01565-z

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