Release of Cytochrome C from Bax Pores at the Mitochondrial Membrane

Abstract How cytochrome C is released from the mitochondria to the cytosol via Bax oligomeric pores, a process which is required for apoptosis, is still a mystery. Based on experimentally measured residue-residue distances, we recently solved the first atomic model for Bax oligomeric pores at the me...

Full description

Bibliographic Details
Main Authors: Mingzhen Zhang, Jie Zheng, Ruth Nussinov, Buyong Ma
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02825-7