The mouse–canine chimeric anti-dog podoplanin antibody P38B exerts antitumor activity in mouse xenograft models

The mouse–canine chimeric anti-dog podoplanin antibody P38B exerts antitumor activity in mouse xenograft models

Podoplanin (PDPN) is a type I transmembrane heavily glycosylated sialoglycoprotein that is expressed in normal tissues such as pulmonary type I alveolar cells, renal podocytes, and lymphatic endothelial cells. PDPN overexpression in cancerous tissue is associated with hematogenous metastasis through...

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Bibliographic Details
Main Authors:	Yukinari Kato, Tomokazu Ohishi, Manabu Kawada, Naoya Maekawa, Satoru Konnai, Shunsuke Itai, Shinji Yamada, Mika K. Kaneko
Format:	Article
Language:	English
Published:	Elsevier 2019-03-01
Series:	Biochemistry and Biophysics Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405580818302577

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