Targeting the Angiotensin II Type 1 Receptor in Cerebrovascular Diseases: Biased Signaling Raises New Hopes

Targeting the Angiotensin II Type 1 Receptor in Cerebrovascular Diseases: Biased Signaling Raises New Hopes

The physiological and pathophysiological relevance of the angiotensin II type 1 (AT<sub>1</sub>) G protein-coupled receptor no longer needs to be proven in the cardiovascular system. The renin–angiotensin system and the AT<sub>1</sub> receptor are the targets of several class...

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Bibliographic Details
Main Authors: Céline Delaitre, Michel Boisbrun, Sandra Lecat, François Dupuis
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
AT<sub>1</sub> receptor
Angiotensin II
cerebrovascular disease
biased agonism
beta-arrestin
RAS
Online Access:https://www.mdpi.com/1422-0067/22/13/6738

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