Exploring electrostatic patterns of human, murine, equine and canine TLR4/MD-2 receptors
Electrostatic interactions between phosphate anions and Toll-like receptor 4 / Myeloid differentiation factor-2 (TLR4/MD-2) protein complexes of human, murine, equine and canine species were computed. Such knowledge can provide mechanistic information about recognising LPS-like ligands, since anioni...
Main Authors: | Jorge Lozano-Aponte, Thomas Scior, Francisco Noé Mendoza Ambrosio, Minerva González-Melchor, Christian Alexander |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-07-01
|
Series: | Innate Immunity |
Online Access: | https://doi.org/10.1177/1753425919894628 |
Similar Items
-
THREE-DIMENSIONAL MAPPING OF DIFFERENTIAL AMINO ACIDS OF HUMAN, MURINE, CANINE AND EQUINE TLR4/MD-2 RECEPTOR COMPLEXES CONFERRING ENDOTOXIC ACTIVATION BY LIPID A, ANTAGONISM BY ERITORAN AND SPECIES-DEPENDENT ACTIVITIES OF LIPID IVA IN THE MAMMALIAN LPS SENSOR SYSTEM
by: Thomas Scior, et al.
Published: (2013-05-01) -
Reviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran, in contrast to species-dependent modulation by lipid IVa
by: Christian Alexander, et al.
Published: (2013-02-01) -
REVIEWING AND IDENTIFYING AMINO ACIDS OF HUMAN, MURINE, CANINE AND EQUINE TLR4 / MD-2 RECEPTOR COMPLEXES CONFERRING ENDOTOXIC INNATE IMMUNITY ACTIVATION BY LPS/LIPID A, OR ANTAGONISTIC EFFECTS BY ERITORAN, IN CONTRAST TO SPECIES-DEPENDENT MODULATION BY LIPID IVA
by: Thomas Scior, et al.
Published: (2013-02-01) -
Contributions of equine TLR4 and MD-2 to Lipid A discrimination
by: Walsh, Catherine Margaret
Published: (2008) -
Recognition of lipid A variants by the TLR4-MD-2 receptor complex
by: Nina eMaeshima, et al.
Published: (2013-02-01)