A method for efficient calculation of diffusion and reactions of lipophilic compounds in complex cell geometry.

A method for efficient calculation of diffusion and reactions of lipophilic compounds in complex cell geometry.

A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distrib...

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Bibliographic Details
Main Authors:	Kristian Dreij, Qasim Ali Chaudhry, Bengt Jernström, Ralf Morgenstern, Michael Hanke
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3166132?pdf=render

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