Gene Expression Profiles Can Predict Panitumumab Monotherapy Responsiveness in Human Tumor Xenograft Models
Background Epidermal growth factor receptor (EGFR)-targeted agents have demonstrated clinical benefit in patients with cancer. Identifying tissue-of-origin-independent predictive biomarkers is important to optimally treat patients. We sought to identify a gene array profile that could predict respo...
Main Authors: | Michael J. Boedigheimer, Daniel J. Freeman, Panteha Kiaei, Michael A. Damore, Robert Radinsky |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-02-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558613800231 |
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