P-glycoprotein Inhibition for Optimal Drug Delivery
P-glycoprotein (P-gp), an efflux membrane transporter, is widely distributed throughout the body and is responsible for limiting cellular uptake and the distribution of xenobiotics and toxic substances. Hundreds of structurally diverse therapeutic agents are substrates to it and it impedes the absor...
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| Format: | Article |
| Language: | English |
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AboutScience Srl
2013-01-01
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| Series: | Drug Target Insights |
| Online Access: | https://doi.org/10.4137/DTI.S12519 |