Pooling individual participant data from randomized controlled trials: Exploring potential loss of information.

BACKGROUND:Pooling individual participant data to enable pooled analyses is often complicated by diversity in variables across available datasets. Therefore, recoding original variables is often necessary to build a pooled dataset. We aimed to quantify how much information is lost in this process an...

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Bibliographic Details
Main Authors: Lennard L van Wanrooij, Marieke P Hoevenaar-Blom, Nicola Coley, Tiia Ngandu, Yannick Meiller, Juliette Guillemont, Anna Rosenberg, Cathrien R L Beishuizen, Eric P Moll van Charante, Hilkka Soininen, Carol Brayne, Sandrine Andrieu, Miia Kivipelto, Edo Richard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232970