Zinc contributes to acute cerebral ischemia-induced blood–brain barrier disruption

Zinc contributes to acute cerebral ischemia-induced blood–brain barrier disruption

Zinc ions are stored in synaptic vesicles and cerebral ischemia triggers their release from the terminals of neurons. Zinc accumulation in neurons has been shown to play an important role in neuronal death following ischemia. However, almost nothing is known about whether zinc is involved in ischemi...

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Bibliographic Details
Main Authors: Zhifeng Qi, Jia Liang, Rong Pan, Wen Dong, Jiangang Shen, Yirong Yang, Yongmei Zhao, Wenjuan Shi, Yumin Luo, Xunming Ji, Ke Jian Liu
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Neurobiology of Disease
Subjects:
Blood–brain barrier
Brain ischemia
Zinc
Matrix metalloproteinases
Tight junction proteins
Cell death
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116301619

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http://www.sciencedirect.com/science/article/pii/S0969996116301619

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