Differential resting-state patterns across networks are spatially associated with Comt and Trmt2a gene expression patterns in a mouse model of 22q11.2 deletion

Differential resting-state patterns across networks are spatially associated with Comt and Trmt2a gene expression patterns in a mouse model of 22q11.2 deletion

Copy number variations (CNV) involving multiple genes are ideal models to study polygenic neuropsychiatric disorders. Since 22q11.2 deletion is regarded as the most important single genetic risk factor for developing schizophrenia, characterizing the effects of this CNV on neural networks offers a u...

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Bibliographic Details
Main Authors: Natalia Gass, Zeru Peterson, Jonathan Reinwald, Alexander Sartorius, Wolfgang Weber-Fahr, Markus Sack, Junfang Chen, Han Cao, Michael Didriksen, Tine Bryan Stensbøl, Gabrielle Klemme, Adam J. Schwarz, Emanuel Schwarz, Andreas Meyer-Lindenberg, Thomas Nickl-Jockschat
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:NeuroImage
Subjects:
22q11.2 deletion
Schizophrenia
Comt
Trmt2a
Functional connectivity
Mouse
Online Access:http://www.sciencedirect.com/science/article/pii/S105381192100793X

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http://www.sciencedirect.com/science/article/pii/S105381192100793X

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