Inhibition of nitric oxide synthase aggravates brain injury in diabetic rats with traumatic brain injury

Inhibition of nitric oxide synthase aggravates brain injury in diabetic rats with traumatic brain injury

Studies have shown that hyperglycemia aggravates brain damage by affecting vascular endothelial function. However, the precise mechanism remains unclear. Male Sprague-Dawley rat models of diabetes were established by a high-fat diet combined with an intraperitoneal injection of streptozotocin. Rat m...

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Bibliographic Details
Main Authors: Wan-Chao Yang, Hong-Ling Cao, Yue-Zhen Wang, Ting-Ting Li, Hong-Yu Hu, Qiang Wan, Wen-Zhi Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
apoptosis; blood-brain barrier; brain edema; diabetes mellitus; inflammation; injury; neurological function; nitric oxide synthase; traumatic brain injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=8;spage=1574;epage=1581;aulast=Yang

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