Protective efficacy of an H5/H7 trivalent inactivated vaccine produced from Re-11, Re-12, and H7-Re2 strains against challenge with different H5 and H7 viruses in chickens

Protective efficacy of an H5/H7 trivalent inactivated vaccine produced from Re-11, Re-12, and H7-Re2 strains against challenge with different H5 and H7 viruses in chickens

We developed an H5/H7 trivalent inactivated vaccine by using Re-11, Re-12, and H7-Re2 vaccine seed viruses, which were generated by reverse genetics and derived their HA genes from A/duck/Guizhou/S4184/2017(H5N6) (DK/GZ/S4184/17) (a clade 2.3.4.4d virus), A/chicken/Liaoning/SD007/2017(H5N1) (CK/LN/S...

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Bibliographic Details
Main Authors: Xian-ying ZENG, Xiao-han CHEN, Shu-jie MA, Jiao-jiao WU, Hong-mei BAO, Shu-xin PAN, Yan-jing LIU, Guo-hua DENG, Jian-zhong SHI, Pu-cheng CHEN, Yong-ping JIANG, Yan-bing LI, Jing-lei HU, Tong LU, Sheng-gang MAO, Xing-fu GUO, Jing-li LIU, Guo-bin TIAN, Hua-lan CHEN
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Journal of Integrative Agriculture
Subjects:
avian influenza
H5/H7 trivalent vaccine
Re-11
Re-12 and H7-Re2 strains
protective efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311920633019

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