High-glucose-induced endothelial cell injury is inhibited by a Peptide derived from human apolipoprotein E.

Although the importance of human apolipoprotein E (apoE) in vascular diseases has clearly been established, most of the research on apoE has focused on its role in cholesterol metabolism. In view of the observation that apoE and its functional domains impact extracellular matrix (ECM) remodeling, we...

Full description

Bibliographic Details
Main Authors: Partha S Bhattacharjee, Tashfin S Huq, Valencia Potter, Anna Young, Ian R Davenport, Richard Graves, Tarun K Mandal, Christian Clement, Harris E McFerrin, Syed Muniruzzaman, Shubha K Ireland, James M Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526597?pdf=render