Hybrid modelling of mechanical cues in cell migration
Many studies stress the crucial importance of the mechanical component in angiogenesis, but still very few models really integrate mechanics. We propose to investigate the importance of mechanical cues for cell migration in this context with a new hybrid continuous-discrete model that describes the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2015-01-01
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| Series: | ITM Web of Conferences |
| Online Access: | http://dx.doi.org/10.1051/itmconf/20150500012 |
| Summary: | Many studies stress the crucial importance of the mechanical component in angiogenesis, but still very few models really integrate mechanics. We propose to investigate the importance of mechanical cues for cell migration in this context with a new hybrid continuous-discrete model that describes the individual migration of contracting cells on an elastic matrix of fibres. The matrix is described as a continuum substrate whereas the cells are described as discrete elements. |
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| ISSN: | 2271-2097 |