Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial Agent
A novel bismuth(III) complex with 2-amino-3-carbomethoxy-4,5,6,7-tetrahydrobenzo[b]thiophene (ACTT) as a ligand have been synthesized. The novel complex was characterized on the basis of its IR, NMR, elemental analysis and MS spectral data. It was found that the ligand behaves as a monodentate chela...
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Slovenian Chemical Society
2020-03-01
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| Series: | Acta Chimica Slovenica |
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| Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/5365 |
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doaj-a395aa7d21fe4e1eb1234f58b319de412020-11-25T02:45:16ZengSlovenian Chemical SocietyActa Chimica Slovenica1318-02071580-31552020-03-0167120321110.17344/acsi.2019.5365780Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial AgentEmmanuel Fondjo Sopbué0Désire André Siéwé1Jean-de-Dieu Tamokou2Steve Endeguele Ekom3Sorel Kamal Dimo Djeukoua4Giscard Doungmo5Mallory E. Walters6Appolinaire Tsopmo7Peter F. W. Simon8Jules Roger Kuiate9Laboratory of Applied Synthetic Organic Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Republic of CameroonLaboratory of Applied Synthetic Organic Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Republic of CameroonResearch Unit of Microbiology and Antimicrobial Substances, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 067 Dschang, Republic of CameroonResearch Unit of Microbiology and Antimicrobial Substances, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 067 Dschang, Republic of CameroonLaboratory of Applied Synthetic Organic Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Republic of CameroonInstitut für Anorganische Chemie, Christian-Albrechts-Universität zu Kiel, Max-Eyth-Str. 2, 24118 Kiel, GermanyDepartment of Chemistry, Carleton University, 1125 Colonel Δby Drive K1S 5B6, Ottawa, Canada +1-613-520-260 Ext 3122Department of Chemistry, Carleton University, 1125 Colonel Δby Drive K1S 5B6, Ottawa, Canada +1-613-520-260 Ext 3122Polymer Chemistry Laboratory, Faculty of Live Sciences, Rhine-Waal University of Applied Sciences, Campus Kleve, Marie-Curie Strasse 1, D-47533 Kleve, GermanyResearch Unit of Microbiology and Antimicrobial Substances, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 067 Dschang, Republic of CameroonA novel bismuth(III) complex with 2-amino-3-carbomethoxy-4,5,6,7-tetrahydrobenzo[b]thiophene (ACTT) as a ligand have been synthesized. The novel complex was characterized on the basis of its IR, NMR, elemental analysis and MS spectral data. It was found that the ligand behaves as a monodentate chelating agent and bonds to the metal ion through the nitrogen atom of the amino group to form the [BiIII(ACTT)6]Cl3 complex. The new complex compound displayed significant antimicrobial activity (MIC = 8–32 μg/mL) against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Shigella flexneri, Candida albicans, Candida tropicalis and Cryptococcus neoformans.https://journals.matheo.si/index.php/ACSi/article/view/5365room temperature synthesisantimicrobialcomplexation reaction2-aminothiophenebismuth |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Emmanuel Fondjo Sopbué Désire André Siéwé Jean-de-Dieu Tamokou Steve Endeguele Ekom Sorel Kamal Dimo Djeukoua Giscard Doungmo Mallory E. Walters Appolinaire Tsopmo Peter F. W. Simon Jules Roger Kuiate |
| spellingShingle |
Emmanuel Fondjo Sopbué Désire André Siéwé Jean-de-Dieu Tamokou Steve Endeguele Ekom Sorel Kamal Dimo Djeukoua Giscard Doungmo Mallory E. Walters Appolinaire Tsopmo Peter F. W. Simon Jules Roger Kuiate Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial Agent Acta Chimica Slovenica room temperature synthesis antimicrobial complexation reaction 2-aminothiophene bismuth |
| author_facet |
Emmanuel Fondjo Sopbué Désire André Siéwé Jean-de-Dieu Tamokou Steve Endeguele Ekom Sorel Kamal Dimo Djeukoua Giscard Doungmo Mallory E. Walters Appolinaire Tsopmo Peter F. W. Simon Jules Roger Kuiate |
| author_sort |
Emmanuel Fondjo Sopbué |
| title |
Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial Agent |
| title_short |
Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial Agent |
| title_full |
Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial Agent |
| title_fullStr |
Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial Agent |
| title_full_unstemmed |
Room Temperature Synthesis and Characterization of Novel Bi(III) Complex with 2-Amino-3-Carbomethoxy-4,5,6,7-Tetrahydrobenzo[B]Thiophene as Potential Antimicrobial Agent |
| title_sort |
room temperature synthesis and characterization of novel bi(iii) complex with 2-amino-3-carbomethoxy-4,5,6,7-tetrahydrobenzo[b]thiophene as potential antimicrobial agent |
| publisher |
Slovenian Chemical Society |
| series |
Acta Chimica Slovenica |
| issn |
1318-0207 1580-3155 |
| publishDate |
2020-03-01 |
| description |
A novel bismuth(III) complex with 2-amino-3-carbomethoxy-4,5,6,7-tetrahydrobenzo[b]thiophene (ACTT) as a ligand have been synthesized. The novel complex was characterized on the basis of its IR, NMR, elemental analysis and MS spectral data. It was found that the ligand behaves as a monodentate chelating agent and bonds to the metal ion through the nitrogen atom of the amino group to form the [BiIII(ACTT)6]Cl3 complex. The new complex compound displayed significant antimicrobial activity (MIC = 8–32 μg/mL) against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Shigella flexneri, Candida albicans, Candida tropicalis and Cryptococcus neoformans. |
| topic |
room temperature synthesis antimicrobial complexation reaction 2-aminothiophene bismuth |
| url |
https://journals.matheo.si/index.php/ACSi/article/view/5365 |
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