Efficient Prostate Cancer Therapy with Tissue-Specific Homing Peptides Identified by Advanced Phage Display Technology
Selective targeting of drugs to tumor cells is a key goal in oncology. Here, we performed an in vivo phage display to identify peptides that specifically target xenografted prostate cancer cells. This yielded three peptide candidates, LN1 (C-TGTPARQ-C), LN2 (C-KNSMFAT-C), and LN3 (C-TNKHSPK-C); each...
Main Authors: | Akinori Wada, Tomoya Terashima, Susumu Kageyama, Tetsuya Yoshida, Mitsuhiro Narita, Akihiro Kawauchi, Hideto Kojima |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-03-01
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Series: | Molecular Therapy: Oncolytics |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2372770519300014 |
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