Correlation of Metal Ions in Diabetic Patients

Introduction: Diabetes Mellitus (DM) presents with insulin deficiency results in raised blood sugars. Metals are the inorganic elements present in very small amounts in the living tissues and play an important role at cellular level and hence are important for life. Macro metals like Magnesium (Mg)...

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Main Authors: Meghali Narayan Kaple, Chandrashekhar C Mahakalkar, Anita Kale, Swati Shambharkar
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2020-05-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/13730/43798_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_GC(Su_SL)_PN(SL).pdf
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spelling doaj-a389129d573245bdbe753affb9c933972020-11-25T03:07:58ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-05-01145BC14BC1610.7860/JCDR/2020/43798.13730Correlation of Metal Ions in Diabetic PatientsMeghali Narayan Kaple0Chandrashekhar C Mahakalkar1Anita Kale2Swati Shambharkar3Associate Professor, Department of Biochemistry, Jawaharlal Nehru Medical College, DMIMS (DU), Sawangi (Meghe), Wardha, Maharashtra, India.Professor, Department of General Surgery, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India.Professor and Head, Department of Biochemistry, Seth GS Medical College and KEM Hospital, Parel, Mumbai, Maharashtra, India.Assistant Professor, Department of Biochemistry, SSPM Medical College, Padve, Maharashtra, India.Introduction: Diabetes Mellitus (DM) presents with insulin deficiency results in raised blood sugars. Metals are the inorganic elements present in very small amounts in the living tissues and play an important role at cellular level and hence are important for life. Macro metals like Magnesium (Mg) are present in large quantity and hence are called as macro nutrients. Aim: To evaluate the correlation of metal ions in Type I and Type II DM. Materials and Methods: It was a prospective study, carried out at Acharya Vinoba Bhave Rural Hospital, JNMC, Sawangi (Meghe), Wardha, Maharashtra, India from January 2017 to January 2019. Total 260 patients were enrolled in the study. The participants were divided in two groups, diabetic and non-diabetic, based on blood sugar levels. The blood samples were analysed for Calcium, Magnesium, Phosphorous and Iron. The comparison was done using student’s t-test. Results: The mean values of Iron (Fe) were 162.17±13.27 μg/dL, Calcium (Ca) 8.21±0.34 mg/dL, Mg 1.49±0.07 mEq/L, and Phosphorous (P) 2.92.±0.49 mg/dL for the whole study population. The various metal levels when compared with the levels of fasting and post prandial blood sugar in Non-diabetic group and Diabetic group the difference was statistically significant for Fe, Ca and P and was not significant for Mg. Conclusion: Fe levels were raised and Ca, Mg and P were depleted in patient suffering from DM.https://jcdr.net/articles/PDF/13730/43798_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_GC(Su_SL)_PN(SL).pdfcalciummacronutrientsmagnesiummicronutrientsphosphorus
collection DOAJ
language English
format Article
sources DOAJ
author Meghali Narayan Kaple
Chandrashekhar C Mahakalkar
Anita Kale
Swati Shambharkar
spellingShingle Meghali Narayan Kaple
Chandrashekhar C Mahakalkar
Anita Kale
Swati Shambharkar
Correlation of Metal Ions in Diabetic Patients
Journal of Clinical and Diagnostic Research
calcium
macronutrients
magnesium
micronutrients
phosphorus
author_facet Meghali Narayan Kaple
Chandrashekhar C Mahakalkar
Anita Kale
Swati Shambharkar
author_sort Meghali Narayan Kaple
title Correlation of Metal Ions in Diabetic Patients
title_short Correlation of Metal Ions in Diabetic Patients
title_full Correlation of Metal Ions in Diabetic Patients
title_fullStr Correlation of Metal Ions in Diabetic Patients
title_full_unstemmed Correlation of Metal Ions in Diabetic Patients
title_sort correlation of metal ions in diabetic patients
publisher JCDR Research and Publications Private Limited
series Journal of Clinical and Diagnostic Research
issn 2249-782X
0973-709X
publishDate 2020-05-01
description Introduction: Diabetes Mellitus (DM) presents with insulin deficiency results in raised blood sugars. Metals are the inorganic elements present in very small amounts in the living tissues and play an important role at cellular level and hence are important for life. Macro metals like Magnesium (Mg) are present in large quantity and hence are called as macro nutrients. Aim: To evaluate the correlation of metal ions in Type I and Type II DM. Materials and Methods: It was a prospective study, carried out at Acharya Vinoba Bhave Rural Hospital, JNMC, Sawangi (Meghe), Wardha, Maharashtra, India from January 2017 to January 2019. Total 260 patients were enrolled in the study. The participants were divided in two groups, diabetic and non-diabetic, based on blood sugar levels. The blood samples were analysed for Calcium, Magnesium, Phosphorous and Iron. The comparison was done using student’s t-test. Results: The mean values of Iron (Fe) were 162.17±13.27 μg/dL, Calcium (Ca) 8.21±0.34 mg/dL, Mg 1.49±0.07 mEq/L, and Phosphorous (P) 2.92.±0.49 mg/dL for the whole study population. The various metal levels when compared with the levels of fasting and post prandial blood sugar in Non-diabetic group and Diabetic group the difference was statistically significant for Fe, Ca and P and was not significant for Mg. Conclusion: Fe levels were raised and Ca, Mg and P were depleted in patient suffering from DM.
topic calcium
macronutrients
magnesium
micronutrients
phosphorus
url https://jcdr.net/articles/PDF/13730/43798_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_GC(Su_SL)_PN(SL).pdf
work_keys_str_mv AT meghalinarayankaple correlationofmetalionsindiabeticpatients
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