Functional significance of allelic variation at methuselah, an aging gene in Drosophila.

BACKGROUND:Longevity and age-specific patterns of mortality are complex traits that vary within and among taxa. Multiple candidate genes for aging have been identified in model systems by extended longevity mutant phenotypes, including the G-protein coupled receptor methuselah (mth) in D. melanogast...

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Bibliographic Details
Main Authors: Annalise B Paaby, Paul S Schmidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2288678?pdf=render