Propofol exerts anti-inflammatory effects in rats with lipopolysaccharide-induced acute lung injury by inhibition of CD14 and TLR4 expression

Propofol exerts anti-inflammatory effects in rats with lipopolysaccharide-induced acute lung injury by inhibition of CD14 and TLR4 expression

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We investigated the effect of propofol (Prop) administration (10 mg kg-1 h-1, intravenously) on lipopolysaccharide (LPS)-induced acute lung injury and its effect on cluster of differentiation (CD) 14 and Toll-like receptor (TLR) 4 expression in lung tissue of anesthetized, venti...

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Bibliographic Details
Main Authors: Ling Ma, Xiu-Ying Wu, Li-Hong Zhang, Wei-Min Chen, Akinori Uchiyama, Takashi Mashimo, Yuji Fujino
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
CD14
Toll-like receptors
Propofol
Lipopolysaccharide
Lung injury
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000300299&lng=en&tlng=en

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