Modeling the Spatiotemporal Dynamics of Light and Heat Propagation for In Vivo Optogenetics
Despite the increasing use of optogenetics in vivo, the effects of direct light exposure to brain tissue are understudied. Of particular concern is the potential for heat induced by prolonged optical stimulation. We demonstrate that high-intensity light, delivered through an optical fiber, is capabl...
Main Authors: | Joseph M. Stujenske, Timothy Spellman, Joshua A. Gordon |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-07-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715006488 |
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