Chalcones Isolated from <i>Arrabidaea brachypoda</i> Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of <i>Staphylococcus aureus</i>

Chalcones Isolated from <i>Arrabidaea brachypoda</i> Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of <i>Staphylococcus aureus</i>

Bacterial resistance to antibiotics has become a public health issue around the world. The present study aimed to evaluate the antibacterial activity of chalcones isolated from flowers of <i>Arrabidaea brachypoda</i>, and their potential as efflux pump inhibitors of <i>Staphylococc...

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Bibliographic Details
Main Authors: Luís Mário Rezende-Júnior, Leila Maria de Sousa Andrade, Antonio Linkoln Alves Borges Leal, Avilnete Belem de Souza Mesquita, Ana Lurdes Portela de Araújo dos Santos, José de Sousa Lima Neto, José Pinto Siqueira-Júnior, Carlos Emídio Sampaio Nogueira, Glenn William Kaatz, Henrique Douglas Melo Coutinho, Natália Martins, Cláudia Quintino da Rocha, Humberto Medeiros Barreto
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Antibiotics
Subjects:
<i>Arrabidaea brachypoda</i>
Chalcone
antimicrobial activity
efflux pumps
efflux pump inhibitors
resistance to antibiotics
Online Access:https://www.mdpi.com/2079-6382/9/6/351

Internet

https://www.mdpi.com/2079-6382/9/6/351

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