Reversible Valproate Hepatotoxicity and Associated Mitochondrial Disease
A 2-year-old boy with seizures complicated by reversible valproate-induced hepatic failure was subsequently found to have mitochondrial polymerase g gene (POLG1) mutations typical of Alpers-Huttenlocher disease, in a study at Newcastle University, UK.
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pediatric Neurology Briefs Publishers
2008-02-01
|
| Series: | Pediatric Neurology Briefs |
| Subjects: | |
| Online Access: | https://www.pediatricneurologybriefs.com/articles/939 |
| Summary: | A 2-year-old boy with seizures complicated by reversible valproate-induced hepatic failure was subsequently found to have mitochondrial polymerase g gene (POLG1) mutations typical of Alpers-Huttenlocher disease, in a study at Newcastle University, UK. |
|---|---|
| ISSN: | 1043-3155 2166-6482 |