Identification of two telomere-proximal fission yeast DNA replication origins constrained by nearby cis-acting sequences to replicate in late S phase [v1; ref status: indexed, http://f1000r.es/SuWYQb]

Telomeres of the fission yeast, Schizosaccharomyces pombe, are known to replicate in late S phase, but the reasons for this late replication are not fully understood. We have identified two closely-spaced DNA replication origins, 5.5 to 8 kb upstream from the telomere itself. These are the most telo...

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Bibliographic Details
Main Authors: Amna Chaudari, Joel A Huberman
Format: Article
Language:English
Published: F1000 Research Ltd 2012-12-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/1-58/v1