The role of valve stiffness in the insurgence of deep vein thrombosis

The role of valve stiffness in the insurgence of deep vein thrombosis

Deep vein thrombosis is the clotting of blood in deep veins. Here, a microfluidic device containing flexible valves fabricated in-situ is used to investigate the effects of blood flow conditions and valve elasticity on thrombus formation, revealing the circumstance under which clotting occurs.

Bibliographic Details
Main Authors: Zoe Schofield, Hosam Alden Baksamawi, Joana Campos, Alessio Alexiadis, Gerard B. Nash, Alexander Brill, Daniele Vigolo
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Communications Materials
Online Access:https://doi.org/10.1038/s43246-020-00066-2
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spelling doaj-a33767ed188743749eee00b8e91af6f02021-09-19T11:22:28ZengNature Publishing GroupCommunications Materials2662-44432020-09-011111010.1038/s43246-020-00066-2The role of valve stiffness in the insurgence of deep vein thrombosisZoe Schofield0Hosam Alden Baksamawi1Joana Campos2Alessio Alexiadis3Gerard B. Nash4Alexander Brill5Daniele Vigolo6School of Chemical Engineering, University of BirminghamSchool of Chemical Engineering, University of BirminghamInstitute of Cardiovascular Sciences, University of BirminghamSchool of Chemical Engineering, University of BirminghamInstitute of Cardiovascular Sciences, University of BirminghamInstitute of Cardiovascular Sciences, University of BirminghamSchool of Chemical Engineering, University of BirminghamDeep vein thrombosis is the clotting of blood in deep veins. Here, a microfluidic device containing flexible valves fabricated in-situ is used to investigate the effects of blood flow conditions and valve elasticity on thrombus formation, revealing the circumstance under which clotting occurs.https://doi.org/10.1038/s43246-020-00066-2
collection DOAJ
language English
format Article
sources DOAJ
author Zoe Schofield
Hosam Alden Baksamawi
Joana Campos
Alessio Alexiadis
Gerard B. Nash
Alexander Brill
Daniele Vigolo
spellingShingle Zoe Schofield
Hosam Alden Baksamawi
Joana Campos
Alessio Alexiadis
Gerard B. Nash
Alexander Brill
Daniele Vigolo
The role of valve stiffness in the insurgence of deep vein thrombosis
Communications Materials
author_facet Zoe Schofield
Hosam Alden Baksamawi
Joana Campos
Alessio Alexiadis
Gerard B. Nash
Alexander Brill
Daniele Vigolo
author_sort Zoe Schofield
title The role of valve stiffness in the insurgence of deep vein thrombosis
title_short The role of valve stiffness in the insurgence of deep vein thrombosis
title_full The role of valve stiffness in the insurgence of deep vein thrombosis
title_fullStr The role of valve stiffness in the insurgence of deep vein thrombosis
title_full_unstemmed The role of valve stiffness in the insurgence of deep vein thrombosis
title_sort role of valve stiffness in the insurgence of deep vein thrombosis
publisher Nature Publishing Group
series Communications Materials
issn 2662-4443
publishDate 2020-09-01
description Deep vein thrombosis is the clotting of blood in deep veins. Here, a microfluidic device containing flexible valves fabricated in-situ is used to investigate the effects of blood flow conditions and valve elasticity on thrombus formation, revealing the circumstance under which clotting occurs.
url https://doi.org/10.1038/s43246-020-00066-2
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