Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity

Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity

Focal cortical seizures result from local and widespread propagation of excitatory activity. Here the authors employ widefield calcium imaging in mouse visual areas to demonstrate that these seizures start as local synchronous activation and then propagate along the connectivity that underlies norma...

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Main Authors: L. Federico Rossi, Robert C. Wykes, Dimitri M. Kullmann, Matteo Carandini
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00159-6
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spelling doaj-a33003a917694f8aa69ec3cd91b17aba2021-01-31T12:30:36ZengNature Publishing GroupNature Communications2041-17232017-08-018111110.1038/s41467-017-00159-6Focal cortical seizures start as standing waves and propagate respecting homotopic connectivityL. Federico Rossi0Robert C. Wykes1Dimitri M. Kullmann2Matteo Carandini3UCL Institute of Ophthalmology, University College LondonUCL Institute of Neurology, University College LondonUCL Institute of Neurology, University College LondonUCL Institute of Ophthalmology, University College LondonFocal cortical seizures result from local and widespread propagation of excitatory activity. Here the authors employ widefield calcium imaging in mouse visual areas to demonstrate that these seizures start as local synchronous activation and then propagate along the connectivity that underlies normal sensory processing.https://doi.org/10.1038/s41467-017-00159-6
collection DOAJ
language English
format Article
sources DOAJ
author L. Federico Rossi
Robert C. Wykes
Dimitri M. Kullmann
Matteo Carandini
spellingShingle L. Federico Rossi
Robert C. Wykes
Dimitri M. Kullmann
Matteo Carandini
Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity
Nature Communications
author_facet L. Federico Rossi
Robert C. Wykes
Dimitri M. Kullmann
Matteo Carandini
author_sort L. Federico Rossi
title Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity
title_short Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity
title_full Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity
title_fullStr Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity
title_full_unstemmed Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity
title_sort focal cortical seizures start as standing waves and propagate respecting homotopic connectivity
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-08-01
description Focal cortical seizures result from local and widespread propagation of excitatory activity. Here the authors employ widefield calcium imaging in mouse visual areas to demonstrate that these seizures start as local synchronous activation and then propagate along the connectivity that underlies normal sensory processing.
url https://doi.org/10.1038/s41467-017-00159-6
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AT robertcwykes focalcorticalseizuresstartasstandingwavesandpropagaterespectinghomotopicconnectivity
AT dimitrimkullmann focalcorticalseizuresstartasstandingwavesandpropagaterespectinghomotopicconnectivity
AT matteocarandini focalcorticalseizuresstartasstandingwavesandpropagaterespectinghomotopicconnectivity
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