Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity

Focal cortical seizures result from local and widespread propagation of excitatory activity. Here the authors employ widefield calcium imaging in mouse visual areas to demonstrate that these seizures start as local synchronous activation and then propagate along the connectivity that underlies norma...

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Bibliographic Details
Main Authors: L. Federico Rossi, Robert C. Wykes, Dimitri M. Kullmann, Matteo Carandini
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00159-6
Description
Summary:Focal cortical seizures result from local and widespread propagation of excitatory activity. Here the authors employ widefield calcium imaging in mouse visual areas to demonstrate that these seizures start as local synchronous activation and then propagate along the connectivity that underlies normal sensory processing.
ISSN:2041-1723