Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification

Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification

The ongoing COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2 has affected all aspects of human society with a special focus on healthcare. Although older patients with preexisting chronic illnesses are more prone to develop severe complications, younger, healthy individuals might also e...

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Bibliographic Details
Main Authors: Vince Kornél Grolmusz, Anikó Bozsik, János Papp, Attila Patócs
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
genetic susceptibility
genotype-phenotype association studies
viral entry
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.653489/full

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