Elevated Neuropeptide Y in Endothelial Dysfunction Promotes Macrophage Infiltration and Smooth Muscle Foam Cell Formation

Elevated Neuropeptide Y in Endothelial Dysfunction Promotes Macrophage Infiltration and Smooth Muscle Foam Cell Formation

Endothelial dysfunction has been linked to vascular inflammation and foam cell formation but the underlying mechanisms still remain unclear. We sought to define the factors inducing inflammation and smooth muscle foam cell formation under endothelial dysfunction using endothelial nitric oxide syntha...

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Bibliographic Details
Main Authors: Bongkun Choi, Min-Kyung Shin, Eun-Young Kim, Ji-Eun Park, Halim Lee, Seong Who Kim, Jae-Kwan Song, Eun-Ju Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
neuropeptide Y (NPY)
pentraxin 3 (PTX3)
smooth muscle foam cell
macrophage
lipid
endothelial nitric oxide synthase (eNOS)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01701/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01701/full

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