CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen

CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen

Hair growth and morphology are generally regulated by the hair cycle in mammals. Fibroblast Growth Factor 5 (FGF5), which is a hair cycle regulator, has a role in regulating the hair cycle during the transition from the anagen phase to the catagen phase, and a hereditary long hair phenotype has been...

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Bibliographic Details
Main Authors: Yuxin Xu, Hongmei Liu, Huilin Pan, Xinyue Wang, Yuxin Zhang, Bing Yao, Nannan Li, Liangxue Lai, Zhanjun Li
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Genes
Subjects:
fgf5
rabbit
hair cycle
long hair
Online Access:https://www.mdpi.com/2073-4425/11/3/297

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