Spontaneous mutations decrease sensitivity of gene expression to random environmental variation in Caenorhabditis elegans.

Biological phenotypes are described as "canalized" if they are robust to minor variation of environment and/or genetic background. The existence of a robust phenotype logically implies that some underlying mechanism must be variable, in the sense of "able to vary", in order to co...

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Bibliographic Details
Main Authors: Charles F Baer, Dee R Denver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2807463?pdf=render