Sox6 directly silences epsilon globin expression in definitive erythropoiesis.
Sox6 is a member of the Sox transcription factor family that is defined by the conserved high mobility group (HMG) DNA binding domain, first described in the testis determining gene, Sry. Previous studies have suggested that Sox6 plays a role in the development of the central nervous system, cartila...
| Format: | Article |
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| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-02-01
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| Series: | PLoS Genetics |
| Online Access: | http://dx.doi.org/10.1371/journal.pgen.0020014 |