A Polysaccharide Purified From Ganoderma lucidum Acts as a Potent Mucosal Adjuvant That Promotes Protective Immunity Against the Lethal Challenge With Enterovirus A71

A Polysaccharide Purified From Ganoderma lucidum Acts as a Potent Mucosal Adjuvant That Promotes Protective Immunity Against the Lethal Challenge With Enterovirus A71

Enterovirus A71 (EV-A71), the pathogen responsible for the seasonal hand-foot-and-mouth epidemics, can cause significant mortality in infants and young children. The vaccine against EV-A71 could potentially prevent virus-induced neurological complications and mortalities occurring due to the high ri...

Full description

Bibliographic Details
Main Authors: Yu-Li Lin, Chiaho Shih, Pei-Yun Cheng, Chiao-Li Chin, An-Ting Liou, Po-Yi Lee, Bor-Luen Chiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
adjuvant
Enterovirus A71
IFN-γ
IL-17
intranasal
mucosal vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.561758/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.561758/full

Similar Items