SMC3 knockdown triggers genomic instability and p53-dependent apoptosis in human and zebrafish cells

<p>Abstract</p> <p>Background</p> <p>The structural maintenance of chromosome 3 (SMC3) protein is a constituent of a number of nuclear multimeric protein complexes that are involved in DNA recombination and repair in addition to chromosomal segregation. Overexpression o...

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Bibliographic Details
Main Author: Ghiselli Giancarlo
Format: Article
Language:English
Published: BMC 2006-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/52