Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cells.
Bone remodeling involves the coordinated actions of osteoclasts, which resorb the calcified bony matrix, and osteoblasts, which refill erosion pits created by osteoclasts to restore skeletal integrity and adapt to changes in mechanical load. Osteoblasts are derived from pluripotent mesenchymal stem...
Main Authors: | Louis M Luttrell, Moahad S Dar, Diane Gesty-Palmer, Hesham M El-Shewy, Katherine M Robinson, Courtney J Haycraft, Jeremy L Barth |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0204197 |
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