Saikosaponin a increases interleukin-10 expression and inhibits scar formation after sciatic nerve injury

Saikosaponin a increases interleukin-10 expression and inhibits scar formation after sciatic nerve injury

Nerve scarring after peripheral nerve injury can severely hamper nerve regeneration and functional recovery. Further, the anti-inflammatory cytokine, interleukin-10, can inhibit nerve scar formation. Saikosaponin a (SSa) is a monomer molecule extracted from the Chinese medicine, Bupleurum. SSa can e...

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Bibliographic Details
Main Authors: Meng-Qiang Huang, Xiao-Yu Cao, Xu-Yi Chen, Ying-Fu Liu, Shuang-Long Zhu, Zhong-Lei Sun, Xian-Bin Kong, Jing-Rui Huo, Sai Zhang, Yun-Qiang Xu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; saikosaponin a; anti-inflammatory factor; inflammation; interleukin-10; nerve scar; peripheral nerve injury; sciatic nerve injury; sciatic functional index; nerve conduction velocity; neuroelectrophysiological function; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=9;spage=1650;epage=1656;aulast=Huang

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