Targeting YAP‐p62 signaling axis suppresses the EGFR‐TKI‐resistant lung adenocarcinoma

Targeting YAP‐p62 signaling axis suppresses the EGFR‐TKI‐resistant lung adenocarcinoma

Abstract Background Despite the progress of advanced target therapeutic agents and immune checkpoint inhibitors, EGFR‐TKI resistance is still one of the biggest obstacles in treating lung cancer. Clinical studies with autophagy inhibitors are actively underway to overcome drug resistance. Methods We...

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Bibliographic Details
Main Authors: Hee Sun Park, Da‐Hye Lee, Da Hyun Kang, Min‐Kyung Yeo, Goeun Bae, Dahye Lee, Geon Yoo, Ju‐Ock Kim, Eunyoung Moon, Yang Hoon Huh, Sang‐Hee Lee, Eun‐Kyeong Jo, Sang Yeon Cho, Jeong Eun Lee, Chaeuk Chung
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Cancer Medicine
Subjects:
autophagy
EGFR‐TKI
lung adenocarcinoma
p62
YAP
Online Access:https://doi.org/10.1002/cam4.3734

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