Racemization of Serine Residues Catalyzed by Dihydrogen Phosphate Ion: A Computational Study
Spontaneous, nonenzymatic reactions in proteins are known to have relevance to aging and age-related diseases, such as cataract and Alzheimer’s disease. Among such reactions is the racemization of Ser residues, but its mechanism in vivo remains to be clarified. The most likely intermediate is an eno...
Main Authors: | Ohgi Takahashi, Ryota Kirikoshi, Noriyoshi Manabe |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-11-01
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Series: | Catalysts |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4344/7/12/363 |
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