Simulating drug penetration during hyperthermic intraperitoneal chemotherapy

Simulating drug penetration during hyperthermic intraperitoneal chemotherapy

Hyperthermic intraperitoneal chemotherapy (HIPEC) is administered to treat residual microscopic disease after debulking cytoreductive surgery. During HIPEC, a limited number of catheters are used to administer and drain fluid containing chemotherapy (41–43 °C), yielding heterogeneities in the perito...

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Bibliographic Details
Main Authors: Daan R. Löke, Roxan F. C. P. A. Helderman, Nicolaas A. P. Franken, Arlene L. Oei, Pieter J. Tanis, Johannes Crezee, H. Petra Kok
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
hyperthermic intrapertioneal chemotherapy (hipec)
computational fluid dynamics (cfd)
computational modeling
cancer biology
drug dynamics
interstitial fluidpressure (ifp)
treatment planning software
Online Access:http://dx.doi.org/10.1080/10717544.2020.1862364

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