Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India

Background. Although choledochal cyst disease is seen predominantly in childhood, it is becomingly increasingly diagnosed in adult patients. Methods. Data of 36 patients with choledochal cysts managed in our institute between January 2010 and December 2018 were retrospectively analyzed. Results. Med...

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Main Authors: Pranav Honnavara Srinivasan, Amudhan Anbalagan, Rajendran Shanmugasundaram, Naganathbabu Obla Lakshmanamoorthy
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Surgery Research and Practice
Online Access:http://dx.doi.org/10.1155/2020/8017460
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spelling doaj-a2af619e758c4c97aaaa53c8f73a85512020-11-25T03:46:42ZengHindawi LimitedSurgery Research and Practice2356-77592356-61242020-01-01202010.1155/2020/80174608017460Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from IndiaPranav Honnavara Srinivasan0Amudhan Anbalagan1Rajendran Shanmugasundaram2Naganathbabu Obla Lakshmanamoorthy3Institute of Surgical Gastroenterology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai, IndiaInstitute of Surgical Gastroenterology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai, IndiaInstitute of Surgical Gastroenterology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai, IndiaInstitute of Surgical Gastroenterology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai, IndiaBackground. Although choledochal cyst disease is seen predominantly in childhood, it is becomingly increasingly diagnosed in adult patients. Methods. Data of 36 patients with choledochal cysts managed in our institute between January 2010 and December 2018 were retrospectively analyzed. Results. Median age at presentation was 37 years (range: 13–72 years). Female-to-male ratio was 3.5 : 1. All patients were symptomatic, and abdominal pain was the most common symptom. 72.2% had other associated conditions. There was a considerable delay from the onset of symptoms to referral, median duration being 348 days. There were 28 cases of type I (77.8%), 5 cases of type IVA (13.9%), and 3 cases of type IVB (8.3%). Cyst excision with Roux-en-Y hepaticojejunostomy was performed in 29 (80.55%) cases. This procedure was combined with a left lateral sectionectomy, left hepatectomy, and radical cholecystectomy in 1, 2, and 1 cases, respectively. Lilly’s technique was used in 2 cases, and cyst excision with hepaticoduodenostomy was performed in 1 case. Early complications were seen in 21 patients (58.3%), and late complications were seen in 5 patients (13.8%). 2 patients were found to have associated malignancies. One patient was detected to have cholangiocarcinoma in the resected liver incidentally, and another patient was diagnosed to have gall bladder cancer intraoperatively. Conclusion. Choledochal cysts should be considered in the differential diagnosis of adults presenting with epigastric or right hypochondrium pain or jaundice. A thorough preoperative evaluation is required. Cyst excision with Roux-en-Y hepaticojejunostomy forms the standard treatment in most cases. Long-term follow-up is essential for management of complications and early detection of malignant change.http://dx.doi.org/10.1155/2020/8017460
collection DOAJ
language English
format Article
sources DOAJ
author Pranav Honnavara Srinivasan
Amudhan Anbalagan
Rajendran Shanmugasundaram
Naganathbabu Obla Lakshmanamoorthy
spellingShingle Pranav Honnavara Srinivasan
Amudhan Anbalagan
Rajendran Shanmugasundaram
Naganathbabu Obla Lakshmanamoorthy
Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India
Surgery Research and Practice
author_facet Pranav Honnavara Srinivasan
Amudhan Anbalagan
Rajendran Shanmugasundaram
Naganathbabu Obla Lakshmanamoorthy
author_sort Pranav Honnavara Srinivasan
title Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India
title_short Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India
title_full Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India
title_fullStr Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India
title_full_unstemmed Management of Choledochal Cysts at a Tertiary Care Centre: A Nine-Year Experience from India
title_sort management of choledochal cysts at a tertiary care centre: a nine-year experience from india
publisher Hindawi Limited
series Surgery Research and Practice
issn 2356-7759
2356-6124
publishDate 2020-01-01
description Background. Although choledochal cyst disease is seen predominantly in childhood, it is becomingly increasingly diagnosed in adult patients. Methods. Data of 36 patients with choledochal cysts managed in our institute between January 2010 and December 2018 were retrospectively analyzed. Results. Median age at presentation was 37 years (range: 13–72 years). Female-to-male ratio was 3.5 : 1. All patients were symptomatic, and abdominal pain was the most common symptom. 72.2% had other associated conditions. There was a considerable delay from the onset of symptoms to referral, median duration being 348 days. There were 28 cases of type I (77.8%), 5 cases of type IVA (13.9%), and 3 cases of type IVB (8.3%). Cyst excision with Roux-en-Y hepaticojejunostomy was performed in 29 (80.55%) cases. This procedure was combined with a left lateral sectionectomy, left hepatectomy, and radical cholecystectomy in 1, 2, and 1 cases, respectively. Lilly’s technique was used in 2 cases, and cyst excision with hepaticoduodenostomy was performed in 1 case. Early complications were seen in 21 patients (58.3%), and late complications were seen in 5 patients (13.8%). 2 patients were found to have associated malignancies. One patient was detected to have cholangiocarcinoma in the resected liver incidentally, and another patient was diagnosed to have gall bladder cancer intraoperatively. Conclusion. Choledochal cysts should be considered in the differential diagnosis of adults presenting with epigastric or right hypochondrium pain or jaundice. A thorough preoperative evaluation is required. Cyst excision with Roux-en-Y hepaticojejunostomy forms the standard treatment in most cases. Long-term follow-up is essential for management of complications and early detection of malignant change.
url http://dx.doi.org/10.1155/2020/8017460
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