Investigation of α-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T

Investigation of α-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T

In this work, α-synuclein amyloid fibrils—the formation of which is a biomarker of Parkinson’s disease—were investigated using the fluorescent probe thioflavin T (ThT). The experimental conditions of protein fibrillogenesis were chosen so that a sufficient num...

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Bibliographic Details
Main Authors:	Anna I. Sulatskaya, Natalia P. Rodina, Maksim I. Sulatsky, Olga I. Povarova, Iuliia A. Antifeeva, Irina M. Kuznetsova, Konstantin K. Turoverov
Format:	Article
Language:	English
Published:	MDPI AG 2018-08-01
Series:	International Journal of Molecular Sciences
Subjects:	α-synuclein amyloid fibrils fibrillogenesis thioflavin T equilibrium microdialysis binding parameters structural polymorphism
Online Access:	http://www.mdpi.com/1422-0067/19/9/2486

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