Unique 5'-P recognition and basis for dG:dGTP misincorporation of ASFV DNA polymerase X.

Unique 5'-P recognition and basis for dG:dGTP misincorporation of ASFV DNA polymerase X.

African swine fever virus (ASFV) can cause highly lethal disease in pigs and is becoming a global threat. ASFV DNA Polymerase X (AsfvPolX) is the most distinctive DNA polymerase identified to date; it lacks two DNA-binding domains (the thumb domain and 8-KD domain) conserved in the homologous protei...

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Bibliographic Details
Main Authors: Yiqing Chen, Jing Zhang, Hehua Liu, Yanqing Gao, Xuhang Li, Lina Zheng, Ruixue Cui, Qingqing Yao, Liang Rong, Jixi Li, Zhen Huang, Jinbiao Ma, Jianhua Gan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5330486?pdf=render

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http://europepmc.org/articles/PMC5330486?pdf=render

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