Investigation of CTNNB1 gene mutations and expression in hepatocellular carcinoma and cirrhosis in association with hepatitis B virus infection

Investigation of CTNNB1 gene mutations and expression in hepatocellular carcinoma and cirrhosis in association with hepatitis B virus infection

Abstract Hepatitis B virus (HBV), along with Hepatitis C virus chronic infection, represents a major risk factor for hepatocellular carcinoma (HCC) development. However, molecular mechanisms involved in the development of HCC are not yet completely understood. Recent studies have indicated that muta...

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Bibliographic Details
Main Authors: Davod Javanmard, Mohammad Najafi, Mohammad Reza Babaei, Mohammad Hadi Karbalaie Niya, Maryam Esghaei, Mahshid Panahi, Fahimeh Safarnezhad Tameshkel, Ahmad Tavakoli, Seyed Mohammad Jazayeri, Hadi Ghaffari, Angila Ataei-Pirkooh, Seyed Hamidreaz Monavari, Farah Bokharaei-Salim
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Infectious Agents and Cancer
Subjects:
HBV
HCC
β-Catenin
CTNNB1
Mutation
Online Access:http://link.springer.com/article/10.1186/s13027-020-00297-5

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